ALDA assumes that the patient has one of the diseases included in the tool and will give a predicted percentage even if the patient has none of the listed diseases. Therefore, if the concordance score is medium-low or low, the patient may not have one of the listed diseases. In addition the tool assumes that neurogenic causes of muscular weakness (Spinal Muscular Atrophy, Charcot-Marie-Tooth, etc.) and autoimmune causes of muscle weakness have already been considered and excluded.